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진료과

  • 연세암병원-종양내과, 간암센터, 췌장 담도암센터, 완화의료센터

전문진료분야

  • <종양내과> 간암, 췌장암, 담도암, 신경내분비종양, 뇌종양, 항암약물치료, 신약치료, 완화의료(통증 및 증상관리)

교육 및 임상 경력

  • 2001.03~2006.02    세브란스병원  인턴,  레지던트
  • 2006.03~2008.02    세브란스병원  혈액종양내과  강사
  • 2008.03~2009.02    연세의대  내과학교실  종양내과  임상연구조교수
  • 2009.03~2015.01    연세의대  내과학교실  종양내과  임상조교수
  • 2015.02~2019.02    연세의대  내과학교실  종양내과  조교수
  • 2019.03~  현    재      연세의대  내과학교실  종양내과  부교수

학력사항

  • 1995.03~2001.02 연세대학교 학사
  • 2004.03~2006.02 연세대학교 석사
  • 2007.09~ 2014.8 연세대학교 박사

논문

  • 진행성 간암의 치료, 대한간암연구회지, 2011년 제11호
  • 전이성 간암의 치료, 대한내과학회지, 2011년 제81권 3호
  • Congenital absence of inferior vena cava as a rare cause of pulmonary thromboembolism
    YONSEI MEDICAL JOURNAL 45/ :947-951,2004
  • 항인지질 증후군 환자에서 동반된 간문맥 혈전증 1예
    대한내과학회지(korean Journal of medcine) 68/1 :99-104,2005
  • A pilot study of trans-arterial injection of 166Holmium-Chitosan complex for treatment of small hepatocellular carcinoma
    YONSEI MEDICAL JOURNAL 46/6 :799-805,2005
  • Cetuximab rescue a patient with non-small cell lung cancer from rapid disease progression during chemotherapy
    ACTA ONCOLOGICA 46/4 :547-549,2007
  • Phase II trial of irinotecan and cisplatin with early concurrent radiotherapy in limited-disease small-cell lung cancer
    CANCER 109/9 :1845-1850,2007
  • Phase II study of erlotinib in advanced non-small-cell lung cancer after failure of gefitinib
    JOURNAL OF CLINICAL ONCOLOGY 25/18 :2528-2533,2007
  • Prognostic impact of resection margin involvement after extended (D2/D3) gastrectomy for advanced gastric cancer: A 15-year experience at a single Institute
    JOURNAL OF SURGICAL ONCOLOGY 95/ :461-468,2007
  • VEGF-specific short hairpin RNA-expressing oncolytic adenovirus elicits potent inhibition of angiogenesis and tumor growth
    MOLECULAR THERAPY 15/2 :295-302,2007
  • Phase I trial of neoadjuvant concurrent chemoradiotherapy with S-1 and weekly irinotecan in locally advanced rectal cancer
    Radiotherapy And Oncology 87/ :361-366,2008
  • Capecitabine and doxorubicin combination chemotherapy as salvage therapy in pretreated advanced gastric cancer
    Cancer Chemotherapy And Pharmacology 61/ :157-165,2008
  • The combination of capecitabine and irinotecan in treating 5-Fluorouracil- and Oxaliplatin-pretreated metastatic colorectal cancer
    Cancer Chemotherapy And Pharmacology 61/ :75-81,2008
  • A single institutional experience of surgically resected thymic epithelial tumors over 10 years - Clinical outcomes and clinicopathologic features
    Oncology Reports 19/ :1525-1531,2008
  • Combination of topotecan and etoposide as a salvage treatment for patients with recurrent small cell lung cancer following irinotecan and platinum first-line chemotherapy
    Cancer Chemotherapy And Pharmacology 61/ :309-313,2008
  • Standardization of the Korean version of Mini-Mental Adjustment to Cancer (K-Mini-MAC) scale: factor structure, reliability and validity
    Psycho-Oncology 17/ :592-597,2008
  • The number of residual metastatic lymph nodes following neoadjuvant chemotherapy predicts survival in patients with stage III NSCLC
    Lung Cancer 60/3 :393-400,2008
  • Phase II Study of Transarterial Holmium-166-Chitosan Complex Treatment in Patients with a Single, Large Hepatocellular Carcinoma
    Oncology 76/1 :1-9,2009
  • Activating mutations within the EGFR kinase domain: a molecular predictor of disease-free survival in resected pulmonary adenocarcinoma
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 135/12 :1647-1654,2009
  • High tumor metabolic activity as measured by fluorodeoxyglucose positron emission tomography is associated with poor prognosis in limited and extensive stage small-cell lung cancer
    Clinical Cancer Research 15/7 :2426-2432,2009
  • Double E1B 19 kDa- and E1B 55 kDa-deleted oncolytic adenovirus in combination with radiotherapy elicits an enhanced anti-tumor effect
    GENE THERAPY 16/ :1111-1121,2009
  • Weekly docetaxel in patients with platinum-refractory metastatic or recurrent squamous cell carcinoma of the head and neck
    CANCER CHEMOTHERAPY AND PHARMACOLOGY 65/1 :27-32,2009
  • Brain metastases from hepatocellular carcinoma: prognostic factors and outcome
    Journal Of Neuro-Oncology 91/3 :307-313,2009
  • Complete Response of Recurrent Squamous Cell Carcinoma of the Lung: Dose the Dose Matter?
    Journal Of Thoracic Oncology 4/1 :141-142,2009
  • Weekly 5-fluorouracil plus cisplatin for concurrent chemoradiotherapy in patients with locally advanced head and neck cancer
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK 32/2 :235-243,2010
  • Frequent central nervous system failure after clinical benefit with epidermal growth factor receptor tyrosine kinase inhibitors in Korean patients with nonsmall-cell lung cancer
    Cancer 116/5 :1336-1343,2010
  • Phase II study of preoperative chemoradiotherapy (CRT) with irinotecan plus S-1 in locally advanced rectal cancer
    Radiotherapy And Oncology 95/3 :303-307,2010
  • Paclitaxel combined with ifosfamide in anthracycline- and docetaxel-pretreated metastatic breast cancer: activity independence of prior docetaxel resistance
    CANCER CHEMOTHERAPY AND PHARMACOLOGY 66/3 :425-431,2010
  • Belotecan for relapsing small-cell lung cancer patients initially treated with an irinotecan-containing chemotherapy: A phase II trial
    Lung Cancer 70/1 :77-81,2010
  • Outcome of Adjuvant Therapy for Gallbladder Cancer
    Oncology 79/3-4 :168-173,2010
  • Prognostic Factors in Small Cell Lung Cancer: A New Prognostic Index in Korean Patients
    Oncology 79/3-4 :293-300,2010
  • MEKK1/MEKK4 are responsible for TRAIL-induced JNK/p38 phosphorylation
    ONCOLOGY REPORTS 25/2 :537-544,2011
  • A phase I study of nimotuzumab in combination with radiotherapy in stages IIB-IV non-small cell lung cancer unsuitable for radical therapy: Korean results
    LUNG CANCER 71/1 :55-59,2011
  • Long-term clinical outcomes of hepatic arterial infusion chemotherapy with cisplatin with or without 5-fluorouracil in locally advanced hepatocellular carcinoma
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 137/4 :659-667,2011
  • Evaluation of Bone Metastasis from Hepatocellular Carcinoma Using 18F-FDG PET/CTand 99mTc-HDP Bone Scintigraphy: Characteristics of Soft Tissue Formation
    Nuclear Medicine and Molecular Imaging 45/3 :203-211,2011
  • Serous Cystic Neoplasm: Do We Have to Wait Till It Causes Trouble?
    Korean Journal Of Hepato-Biliary-Pancreatic Surgery(한국간담췌외과학회지) 15/2 :134-138,2011
  • Prognostic value of 18F-FDG PET for hepatocellular carcinoma patients treated with sorafenib
    LIVER INTERNATIONAL 31/8 :1144-1149,2011
  • 진행성 간암에서 전신 요법
    대한간암연구학회지 11/1 :33-39,2011
  • 전이성 간암의 치료
    Korean J Med 81/3 :279-288,2011
  • 항암화학요법을 받는 환자의 구강관리 프로토콜개발 및 적용효과
    임상간호연구 17/1 :113-122,2011
  • Potential Contribution of Preoperative Neoadjuvant Concurrent Chemoradiation Therapy on Margin-Negative Resection in Borderline Resectable Pancreatic Cancer
    JOURNAL OF GASTROINTESTINAL SURGERY 16/3 :509-517,2012
  • Gemcitabine and oxaliplatin with or without erlotinib in advanced biliary-tract cancer: a multicentre, open-label, randomised, phase 3 study
    LANCET ONCOLOGY 13/2 :181-188,2012
  • In Vitro Adenosine Triphosphate-Based Chemotherapy Response Assay (ATP-CRA) in Solid Pseudopapillary Tumor of the Pancreas
    PANCREAS 41/3 :498-500,2012
  • Sorafenib versus cytotoxic chemotherapy for patients with advanced hepatocellular carcinoma: a retrospective, single-institution study
    INVESTIGATIONAL NEW DRUGS 30/3 :1150-1157,2012
  • 동영상 운동프로그램이 항암 화학요법을 받는 암환자의 피로와 신체기능 및 정서상태에 미치는 효과
    임상간호연구 18/3 :368-380,2012
  • Randomized controlled trial of standardized education and telemonitoring for pain in outpatients with advanced solid tumors
    SUPPORTIVE CARE IN CANCER 21/6 :1751-1759,2013
  • Prognostic Value of 18F-Fluorodeoxyglucose Positron Emission Tomography in Patients with Resectable Pancreatic Cancer
    YONSEI MEDICAL JOURNAL 54/6 :1377-1383,2013
  • Better Outcome of XELOX Chemotherapy in Patients with Advanced Intestinal-Type Adenocarcinoma of the Ampulla of Vater
    TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 231/ :21-28,2013
  • Two Cases of Humoral Hypercalcemia of Malignancy in Metastatic Cholangiocarcinoma
    Cancer Research and Treatment 45/2 :145-149,2013
  • Prolonged clinical benefit from the maintenance hormone therapy in patients with metastatic breast cancer
    BREAST 22/6 :1205-1209,2013
  • Prognostic Value of Metabolic Tumor Volume and Total Lesion Glycolysis on Preoperative 18F-FDG PET/CT in Patients with Pancreatic Cancer
    JOURNAL OF NUCLEAR MEDICINE 55/6 :898-904,2014
  • Prognostic Significance of Volume-Based FDG PET/CT Parameters in Patients with Locally Advanced Pancreatic Cancer Treated with Chemoradiation Therapy
    YONSEI MEDICAL JOURNAL 55/6 :1498-1506,2014
  • Hepatocellular carcinoma specific graded prognostic assessment can predict outcomes for patients with brain metastases from hepatocellular carcinoma
    JOURNAL OF NEURO-ONCOLOGY 120/1 :199-207,2014
  • A phase II study of the efficacy and safety of the combination therapy of the MEK inhibitor refametinib (BAY 86-9766) plus sorafenib for Asian patients with unresectable hepatocellular carcinoma
    CLINICAL CANCER RESEARCH 20/23 :5976-5985,2014
  • 18F-FDG PET/CT in hepatocellular carcinoma: Detection of bone metastasis and prediction of prognosis
    NUCLEAR MEDICINE COMMUNICATIONS 36/3 :226-233,2015
  • Ratio of phosphorylated HSP27 to nonphosphorylated HSP27 biphasically acts as a determinant of cellular fate in gemcitabine-resistant pancreatic cancer cells
    CELLULAR SIGNALLING 27/4 :807-817,2015
  • Prognostic significance of standardized uptake value on preoperative 18F-FDG PET/CT in patients with ampullary adenocarcinoma
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 42/6 :841-847,2015
  • Pain Palliation in Patients with Bone Metastases Using Magnetic Resonance-Guided Focused Ultrasound with Conformal Bone System: A Preliminary Report
    YONSEI MEDICAL JOURNAL 56/2 :503-509,2015
  • Molecular Subgroup Analysis of Clinical Outcomes in a Phase 3 Study of Gemcitabine and Oxaliplatin with or without Erlotinib in Advanced Biliary Tract Cancer
    TRANSLATIONAL ONCOLOGY 8/1 :40-46,2015
  • Prediction of short- and long-term survival for advanced cancer patients after ICU admission
    SUPPORTIVE CARE IN CANCER 23/6 :1647-1655,2015
  • Hepatitis B viral load predicts survival in hepatocellular carcinoma patients treated with sorafenib
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 30/6 :1024-1031,2015
  • Results of a Phase II Study to Evaluate the Efficacy of Docetaxel and Carboplatin in Metastatic Malignant Melanoma Patients Who Failed First-Line Therapy Containing Dacarbazine
    CANCER RESEARCH AND TREATMENT 74/4 :781-789,2015
  • Pseudoprogression in glioblastoma patients: the impact of extent of resection
    JOURNAL OF NEURO-ONCOLOGY 126/3 :559-566,2016
  • Survivin silencing and TRAIL expression using oncolytic adenovirus increase anti-tumorigenic activity in gemcitabine-resistant pancreatic cancer cells.
    APOPTOSIS 21/3 :351-364,2016
  • Characteristics of Venous Thromboembolism in Pancreatic Adenocarcinoma in East Asian Ethnics : A Large Population-Based Observational Study.
    MEDICINE 95/17 :e3472-,2016
  • Prime-boost immunization by both DNA vaccine and oncolytic adenovirus expressing GM-CSF and shRNA of TGF-β2 induces anti-tumor immune activation
    ONCOTARGET 8/9 :15,858-15,877,2017
  • Down-regulation of TGF-β expression sensitizes the resistance of hepatocellular carcinoma cells to sorafenib
    YONSEI MEDICAL JOURNAL 58/5 :899-909,2017
  • Long-term outcomes of concomitant chemoradiotherapy with temozolomide for newly diagnosed glioblastoma patients A single-center analysis
    MEDICINE 96/27 :e7422-,2017
  • Outpatient Palliative Care and Aggressiveness of End-of-Life Care in Patients with Metastatic Colorectal Cancer.
    AMERICAN JOURNAL OF HOSPICE & PALLIATIVE MEDICINE 35/1 :166-172,2018
  • Multiple systemic extraneural metastasis of glioblastoma
    Chirurgia 31/1 :39-43,2018
  • TGF-β downregulation-induced cancer cell death is finely regulated by SAPKs signaling cascade
    EXPERIMENTAL AND MOLECULAR MEDICINE 50/ :162-180,2018
  • Distinct immunological properties of the two histological subtypes of adenocarcinoma of the ampulla of Vater
    CANCER IMMUNOLOGY IMMUNOTHERAPY 68/3 :443-454,2019

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