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진료과

  • 의과대학-내과학교실, 내분비내과, 당뇨병센터, 내분비내과

전문진료분야

  • [강의분야] 대사, 면역학 [연구관심분야] ○ 자가포식, 세포 사멸 ○ 대사/내분비학 ○ 면역/염증

진료시간표

인터넷진료예약
의사시간표
진료시간
오전 본관
오후

논문

  • IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: A key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death
    JOURNAL OF IMMUNOLOGY 166/7 :4481-4489,2001
  • IFNg sensitizes ME-180 human cervical cancer cells to TNFa-induced apoptosis by inhibiting cytoprotective NF-kB activation
    FEBS LETTERS 495/1-2 :66-70,2001
  • IFN gamma/TNF alpha synergism in MHC class II induction: effect of nicotinamide on MHC class II expression but not on islet-cell apoptosis
    DIABETOLOGIA 45/3 :385-393,2002
  • Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis
    ONCOGENE 21/20 :3139-3148,2002
  • Identification and functional characterization of a novel mutation of hepatocyte nuclear factor-1 alpha gene in a Korean family with MODY3
    DIABETOLOGIA 46/5 :721-727,2003
  • Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes
    DIABETOLOGIA 46/9 :1220-1227,2003
  • Resistance of mitochondrial DNA-depleted cells against cell death - Role of mitochondrial superoxide dismutase
    JOURNAL OF BIOLOGICAL CHEMISTRY 279/9 :7512-7520,2004
  • Catecholamine cardiomyopathy associated with paraganglioma rescued by percutaneous cardiopulmonary support - Inverted takotsubo contractile pattern
    CIRCULATION JOURNAL 71/12 :1993-1995,2007
  • NF-kappa B Activation in Hypothalamic Pro-opiomelanocortin Neurons Is Essential in Illness- and Leptin-induced Anorexia
    The Journal of biological chemistry 285/13 :9706-9715,2010
  • Germline mutation of Glu70Lys is highly frequent in Korean patients with von Hippel-Lindau (VHL) disease
    JOURNAL OF HUMAN GENETICS 59/9 :488-493,2014
  • Chronic HMGCR/HMG-CoA Reductase Inhibitor Treatment Contributes to Dysglycemia by Upregulating Hepatic Gluconeogenesis through Autophagy Induction.
    AUTOPHAGY 11/11 :2089-2101,2015
  • Gut Microbiota and Metabolic Disorders
    Diabetes and Metabolism Journal 39/3 :198-203,2015
  • FGF21 as a mediator of adaptive responses to stress and metabolic benefits of anti-diabetic drugs
    JOURNAL OF ENDOCRINOLOGY 226/1 :R1-R16,2015
  • Age-dependent gait abnormalities in mice lacking the Rnf170 gene linked to human autosomal-dominant sensory ataxia
    HUMAN MOLECULAR GENETICS 24/25 :7196-7206,2015
  • Effect of mitochondrial stress on the systemic metabolism
    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 1350/- :61-65,2015
  • New mechanisms of metformin action: Focusing on mitochondria and the gut
    JOURNAL OF DIABETES INVESTIGATION 6/6 :600-609,2015
  • CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis
    SCIENTIFIC REPORTS 6/27938 :1-13,2016
  • Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis
    AUTOPHAGY 12/8 :1,390-1,403,2016
  • Role of mitochondrial function in cell death and metabolism
    FRONTIERS IN BIOSCIENCE-LANDMARK 21/ :1,233-1,244,2016
  • p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
    NATURE COMMUNICATIONS 7/ :12,030-,2016
  • The orphan nuclear receptor erraγ regulates hepatic cb1 receptor-mediated fibroblast growth factor 21 gene expression
    PLOS ONE 11/7 :e0159425-,2016
  • Secretagogin affects insulin secretion in pancreatic β-cells by regulating actin dynamics and focal adhesion.
    BIOCHEMICAL JOURNAL 473/ :1,791-1,803,2016
  • Autophagy is a major regulator of beta cell insulin homeostasis
    DIABETOLOGIA 59/ :1,480-1,491,2016
  • Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease
    AUTOPHAGY 12/5 :784-800,2016
  • Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance
    ARCHIVES OF PHARMACAL RESEARCH 39/99 :1503-1518,2016
  • Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated mediated activation of autophagy and NLRP3 inflammasome inhibition
    AUTOPHAGY 13/10 :1,767-1,781,2017
  • Alterations in gut microbiota and immunity by dietary fat
    YONSEI MEDICAL JOURNAL 58/6 :1,083-1,091,2017
  • Obesogenic diet-induced gut barrier dysfunction and pathobiont expansion aggravate experimental colitis
    PLOS ONE 12/11 :e0187515-,2017
  • A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes.
    NATURE COMMUNICATIONS 9/1 :1,438-,2018
  • Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice
    SCIENTIFIC REPORTS 8/1 :6,789-6,802,2018
  • The Role of Autophagy in Systemic Metabolism and Human-Type Diabetes
    MOLECULES AND CELLS 41/1 :11-17,2018
  • Pathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic Approaches
    Frontiers in Endocrinology 9/ :485-499,2018
  • Nonsynonymous Variants in PAX4 and GLP1R Are Associated With Type 2 Diabetes in an East Asian Population
    DIABETES 67/9 :1,892-1,902,2018

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