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진료과

  • 의과대학-내과학교실, 혈액내과, 혈액암센터, 암예방센터, 혈액내과

전문진료분야

  • <혈액내과> 골수형성이상증후군,백혈병,혈액암

진료시간표

인터넷진료예약
의사시간표
진료시간
오전 암병원 암병원
오후 암병원 암병원

교육 및 임상 경력

  • 2002-2004  연세의대  내과학교실  강사
  • 2004-2006  연세의대  내과학교실  전임강사
  • 2006-2011  연세의대  내과학교실  조교수
  • 2011-2017    연세의대  내과학교실  부교수
  • 2017-현재      연세의대  내과학교실  교수

학술관련경력

  • 내과전문의 (2002년)
  • 혈액종양내과 분과전문의 (2004년)
  • 대한혈핵학회 학술위원(2004년-현재)
  • 대한혈액학회 학술간사역임(2005-2008년)
  • 한국혈전지혈학회 회원이사(2006년-현재)
  • 아시아태평양조혈모세포이식학회 준비위원회 학술간사
  • 대한수혈학회 무임소이사
  • 한국조혈모세포은행협회 학술간사

주요 관심분야

  • 혈액종양
  • 출혈성질환
  • 빈혈

학력사항

  • 연세의대 의학과 학사 (1994년)
  • 연세의대 내과학 석사 (2001년)
  • 연세의대 내과학 박사 (2006년)

논문

  • Targeted next generation sequencing can serve as an alternative to conventional tests in myeloid neoplasms
    PLOS ONE 14/3 :e0212228-,2019
  • HBsAg-Negative, Anti-HBc?Negative Patients Still Have a Risk of Hepatitis B Virus?Related Hepatitis after Autologous Stem Cell Transplantation for Multiple Myeloma or Malignant Lymphoma
    CANCER RESEARCH AND TREATMENT 50/4 :1,121-1,129,2018
  • Platelet storage induces accelerated desialylation of platelets and increases hepatic thrombopoietin production
    JOURNAL OF TRANSLATIONAL MEDICINE 16/1 :199-208,2018
  • Clinical impact of early recovery of peripheral blood absolute lymphocyte count after frontline autologous stem cell transplantation for diffuse large B-cell lymphoma
    HEMATOLOGICAL ONCOLOGY 35/4 :465-471,2017
  • 조혈모세포이식 기간 중 혈액암 환자들의 운동인식
    한국체육학회지 56/6 :527-540,2017
  • Pretreatment Epstein-Barr virus DNA in whole blood is a prognostic marker in peripheral T-cell lymphoma
    ONCOTARGET 8/54 :92,312-92,323,2017
  • Programmed cell death 1 expression is associated with inferior survival in patients with primary central nervous system lymphoma
    ONCOTARGET 8/50 :87,317-87,328,2017
  • Clinical characteristics and treatment outcomes of isolated myeloid sarcoma without bone marrow involvement: a single-institution experience
    Blood Research 51/3 :184-192,2017
  • Epidemiology and Risk Factors for Invasive Fungal Diseases among Allogeneic Hematopoietic Stem Cell Transplant Recipients in Korea: Results of "RISK" Study
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 23/10 :1,773-1,779,2017
  • Salvage therapy for acute chemorefractory leukemia by allogeneic stem cell transplantation: the Korean experience
    ANNALS OF HEMATOLOGY 96/4 :605-615,2017
  • Factors associated with pulmonary toxicity after myeloablative conditioning using fractionated total body irradiation
    Radiation Oncology Journal 35/03 :257-267,2017
  • 의과대학 수업수준에서의 준거설정 사례 연구
    교육문화연구 23/2 :189-209,2017
  • Targeting AMPK-ULK1-mediated autophagy for combating BET inhibitor resistance in acute myeloid leukemia stem cells.
    AUTOPHAGY 13/4 :761-762,2017
  • Prognostic significance of interventricular septal thickness in patients with AL amyloidosis
    LEUKEMIA RESEARCH 60/ :36-43,2017
  • The prognostic role of CD68 and FoxP3 expression in patients with primary central nervous system lymphoma
    ANNALS OF HEMATOLOGY 96/7 :1,163-1,173,2017
  • AMPK-ULK1-mediated autophagy confers resistance to BET inhibitor JQ1 in acute myeloid leukemia stem cells
    CLINICAL CANCER RESEARCH 23/11 :2,781-2,794,2017
  • Decitabine as a First-Line Treatment for Older Adults Newly Diagnosed with Acute Myeloid Leukemia
    YONSEI MEDICAL JOURNAL 58/1 :35-42,2017
  • Cytogenetic profiles of 2806 patients with acute myeloid leukemia-a retrospective multicenter nationwide study
    ANNALS OF HEMATOLOGY 95/8 :1,223-1,232,2016
  • Prognostic Impact of IPSS-R and Chromosomal Translocations in 751 Korean Patients with Primary Myelodysplastic Syndrome
    PLOS ONE 11/11 :e0166245-,2016
  • Chronic Myeloid Leukemia With Rare Variant b2a3 (e13a3) BCR-ABL1 Fusion
    ANNALS OF LABORATORY MEDICINE 36/3 :287-289,2016
  • Risk factors associated with early mortality in patients with multiple myeloma who were treated upfront with a novel agents containing regimen
    BMC CANCER 16/ :613-622,2016
  • The role of upfront autologous stem cell transplantation in high-risk younger patients with primary central nervous system lymphoma
    BRITISH JOURNAL OF HAEMATOLOGY 174/3 :444-453,2016
  • The different roles of molecular classification according to upfront autologous stem cell transplantation in advanced-stage diffuse large B cell lymphoma patients with elevated serum lactate dehydrogenase.
    ANNALS OF HEMATOLOGY 95/9 :1491-1501,2016
  • Effect of major histocompatibility complex haplotype matching by C4 and MICA genotyping on acute graft versus host disease in unrelated hematopoietic stem cell transplantation
    HUMAN IMMUNOLOGY 77/2 :176-183,2016
  • Selection of a mobilization regimen for multiple myeloma based on the response to induction therapy: granulocyte-colony stimulating factor (G-CSF) alone versus high-dose cyclophosphamide plus G-CSF
    LEUKEMIA & LYMPHOMA 57/6 :1389-1397,2016
  • Pretreatment Lymphopenia, Poor Performance Status, and Early Courses of Therapy Are Risk Factors for Severe Bacterial Infection in Patients with Multiple Myeloma during Treatment with Bortezomib-based Regimens
    JOURNAL OF KOREAN MEDICAL SCIENCE 31/4 :510-518,2016
  • A new prognostic model using absolute lymphocyte count in patients with primary central nervous system lymphoma ☆
    EUROPEAN JOURNAL OF CANCER 57/- :127-135,2016
  • Enhanced autophagy in cytarabine arabinoside-resistant U937 leukemia cells and its potential as a target for overcoming resistance.
    MOLECULAR MEDICINE REPORTS 13/4 :3433-3440,2016
  • High pre-transplant serum ferritin and busulfan-thiotepa conditioning regimen as risk factors for hepatic sinusoidal obstructive syndrome after autologous stem cell transplantation in patients with malignant lymphoma.
    LEUKEMIA & LYMPHOMA 57/1 :51-57,2016
  • Radiotherapy as an effective treatment modality for follicular lymphoma: a single institution experience
    Radiation Oncology Journal 33/4 :310-319,2015
  • Tear Cytokines as Biomarkers for Chronic Graft-versus-Host Disease
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 21/12 :2079-2085,2015
  • Prediction of survival by applying current prognostic models in diffuse large B-cell lymphoma treated with R-CHOP followed by autologous transplantation
    Blood Research 50/3 :160-166,2015
  • Single monosomy as a relatively better survival factor in acute myeloid leukemia patients with monosomal karyotype
    BLOOD CANCER JOURNAL 5/e358 :1-7,2015
  • Azacitidine Pre-Treatment Followed by Reduced-Intensity Stem Cell Transplantation in Patients with Higher-Risk Myelodysplastic Syndrome
    ACTA HAEMATOLOGICA 134/1 :40-48,2015
  • Induction of cytosine arabinoside-resistant human myeloid leukemia cell death through autophagy regulation by hydroxychloroquine
    BIOMEDICINE & PHARMACOTHERAPY 73/- :87-96,2015
  • Hemophagocytic Lymphohistiocytosis after Lung Transplantation
    Korean journal of critical care medicine (대한중환자의학회지) 30/1 :38-41,2015
  • Early CMV replication and subsequent chronic GVHD have a significant anti-leukemic effect after allogeneic HSCT in acute myeloid leukemia
    ANNALS OF HEMATOLOGY 94/2 :275-282,2015
  • The Modified Glasgow Prognostic Scores as a Predictor in Diffuse Large B Cell Lymphoma Treated with R-CHOP Regimen
    YONSEI MEDICAL JOURNAL 55/6 :1568-1575,2014
  • Multicenter study evaluating the impact of hypomethylating agents as bridging therapy to hematopoietic stem cell transplantation in myelodysplastic syndromes
    INTERNATIONAL JOURNAL OF HEMATOLOGY 99/5 :635-643,2014
  • The role of radiotherapy in the management of POEMS syndrome
    RADIATION ONCOLOGY 9/ :-,2014
  • Diffuse large B-cell lymphoma with histone H3 trimethylation at lysine 27: Another poor prognostic phenotype independent of c-Myc/Bcl2 coexpression
    HUMAN PATHOLOGY 45/10 :2043-2050,2014
  • Monoclonal and polyclonal gammopathy measured by serum free light chain and immunofixation subdivide the clinical outcomes of diffuse large B-cell lymphoma according to molecular classification
    ANNALS OF HEMATOLOGY 93/11 :1867-1877,2014
  • Deferasirox improves hematologic and hepatic function with effective reduction of serum ferritin and liver iron concentration in transfusional iron overload patients with myelodysplastic syndrome or aplastic anemia
    TRANSFUSION 54/6 :1542-1551,2014
  • Role of induction and consolidation chemotherapy in elderly acute myeloid leukemia patients
    INTERNATIONAL JOURNAL OF HEMATOLOGY 100/2 :141-151,2014
  • Serum microRNA-21 as a potential biomarker for response to hypomethylating agents in myelodysplastic syndromes
    PLOS ONE 9/Issue 2 :e86933-,2014
  • Early response to high-dose methotrexate, vincristine, and procarbazine chemotherapy-adapted strategy for primary CNS lymphoma: no consolidation therapy for patients achieving early complete response.
    ANNALS OF HEMATOLOGY 93/2 :211-219,2014
  • High-Dose Etoposide Plus Granulocyte Colony-Stimulating Factor as an Effective Chemomobilization Regimen for Autologous Stem Cell Transplantation in Patients with Non-Hodgkin Lymphoma Previously Treated with CHOP-based Chemotherapy: A Study from the
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 20/1 :73-79,2014
  • Clinical Outcomes and Prognostic Factors of Empirical Antifungal Therapy with Itraconazole in the Patients with Hematological Malignancies: A Prospective Multicenter Observational Study in Korea
    YONSEI MEDICAL JOURNAL 55/1 :9-18,2014
  • Success Rate and Risk Factors for Failure of Empirical Antifungal Therapy with Itraconazole in Patients with Hematological Malignancies: A Multicenter, Prospective, Open-Label, Observational Study in Korea
    JOURNAL OF KOREAN MEDICAL SCIENCE 29/1 :61-68,2014
  • The relationship between the success rate of empirical antifungal therapy with intravenous itraconazole and clinical parameters, including plasma levels of itraconazole, in immunocompromised patients receiving itraconazole oral solution as prophylax
    ANNALS OF HEMATOLOGY 93/1 :33-42,2014
  • Incidence and risk factors for carbapenem- and multidrug-resistant Acinetobacter baumannii bacteremia in hematopoietic stem cell transplantation recipients
    SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES 46/ :81-88,2014
  • 항체동정검사상 범응집반응을 보인 환자에서 최소반응강도 적혈구제제의 수혈 효과
    대한수혈학회지 24/1 :48-57,2013
  • Patterns of care and treatment outcomes for primary thyroid lymphoma: a single institution study
    Radiation oncology journal 31/4 :177-184,2013
  • Comparative analysis between azacitidine and decitabine for the treatment of myelodysplastic syndromes
    BRITISH JOURNAL OF HAEMATOLOGY 161/3 :339-347,2013
  • Karyotypic change between diagnosis and relapse as a predictor of salvage therapy outcome in AML patients.
    Blood Research 48/1 :24-30,2013
  • Diagnostic Accuracy of Cerebrospinal Fluid (CSF) Cytology in Metastatic Tumors: An Analysis of Consecutive CSF Samples
    KOREAN JOURNAL OF PATHOLOGY 47/6 :563-568,2013
  • Influence of enzyme and transporter polymorphisms on trough imatinib concentration and clinical response in chronic myeloid leukemia patients
    ANNALS OF ONCOLOGY 24/3 :756-760,2013
  • Fludarabine, cytarabine, and attenuated-dose idarubicin (m-FLAI) combination therapy for elderly acute myeloid leukemia patients
    AMERICAN JOURNAL OF HEMATOLOGY 88/1 :10-15,2013
  • Risk Factors for Progression from Cytomegalovirus Viremia to Cytomegalovirus Disease after Allogeneic Hematopoietic Stem Cell Transplantation
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 18/6 :881-886,2012
  • Patient counseling program to improve the compliance to imatinib in chronic myeloid leukemia patients
    MEDICAL ONCOLOGY 29/2 :1179-1185,2012
  • Aurora A kinase expression is increased in leukemia stem cells, and a selective Aurora A kinase inhibitor enhances Ara-C-induced apoptosis in acute myeloid leukemia stem cells
    대한혈액학회지 47/3 :178-185,2012
  • Myeloperoxidase expression in acute myeloid leukemia helps identifying patients to benefit from transplant.
    YONSEI MEDICAL JOURNAL 53/3 :530-536,2012
  • A randomized trial of mesenchymal stem cells in multiple system atrophy.
    ANNALS OF NEUROLOGY 72/1 :32-40,2012
  • Clinical significance of B cell-activating factor (BAFF) and a proliferation-inducing ligand (APRIL) in acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    대한혈액학회지 46/3 :175-179,2011
  • Trough plasma imatinib levels are correlated with optimal cytogenetic responses at 6 months after treatment with standard dose of imatinib in newly diagnosed chronic myeloid leukemia
    LEUKEMIA & LYMPHOMA 52/6 :1024-1029,2011
  • Lymphopenia is an important prognostic factor in peripheral T-cell lymphoma (NOS) treated with anthracycline-containing chemotherapy
    JOURNAL OF HEMATOLOGY & ONCOLOGY 4/- :34-,2011
  • Cytogenetic features of 5q deletion and 5q-syndrome in myelodysplastic syndrome in Korea; marker chromosomes proved to be chromosome 5 with interstitial deletion by fluorescence in situ hybridization
    Cancer Genetics and Cytogenetics 203/2 :193-202,2010
  • Inhibition of CK2 alpha and PI3K/Akt Synergistically Induces Apoptosis of CD34(+)CD38(-) Leukaemia Cells while Sparing Haematopoietic Stem Cells
    Anticancer Research 30/11 :4625-4634,2010
  • Myeloperoxidase Expression as a Potential Determinant of Parthenolide-Induced Apoptosis in Leukemia Bulk and Leukemia Stem Cells
    Journal Of Pharmacology And Experimental Therapeutics 335/ :389-400,2010
  • AURORA-A KINASE INHIBITION ENHANCES THE CYTOSINE ARABINOSIDE-INDUCED CELL DEATH IN LEUKEMIA CELLS THROUGH APOPTOSIS AND MITOTIC CATASTROPHE
    Haematologica-The Hematology Journal 95/ :1771-,2010
  • Therapy-related myelodysplastic syndrome with der(17)t(12;17)(q13;p13) as a new recurrent cytogenetic abnormality after treatment for chronic lymphocytic leukemia
    Leukemia Research 33/7 :1001-1004,2009
  • Natural polyphenols antagonize the antimyeloma activity of proteasome inhibitor bortezomib by direct chemical interaction
    British Journal Of Haematology 146/3 :270-281,2009
  • A successful treatment of relapsed primary CNS lymphoma patient with intraventricular rituximab followed by high-dose chemotherapy with autologous stem cell rescue
    Yonsei Medical Journal 50/2 :280-283,2009
  • Complete Remission Status before Autologous Stem Cell Transplantation Is an Important Prognostic Factor in Patients with Multiple Myeloma Undergoing Upfront Single Autologous Transplantation
    Biology Of Blood And Marrow Transplantation 15/4 :463-470,2009
  • Detection of FUS-ERG chimeric transcript in two cases of acute myeloid leukemia with t(16;21)(p11.2;q22) with unusual characteristics
    Cancer Genetics and Cytogenetics 194/2 :111-118,2009
  • Concomitant t(3;3)(q21;q26), trisomy 19, and E255V mutation associated with imatinib mesylate resistance in chronic myelogenous leukemia
    Cancer Genetics and Cytogenetics 190/ :46-48,2009
  • Two case reports of 1q triplication in myeloproliferative neoplasms
    Cancer Genetics and Cytogenetics 191/2 :111-112,2009
  • 동종 조혈모세포이식 후 다발성 근염으로 발현된 만성 이식편대숙주반응
    대한내과학회지 76/1 :110-113,2009
  • Transfusion-Associated Iron Overload as an Adverse Risk Factor for Transplantation Outcome in Patients Undergoing Reduced-Intensity Stem Cell Transplantation for Myeloid Malignancies
    Acta Haematologica 120/3 :182-189,2008
  • 8번 염색체 사체성을 보인 급성단구성백혈병 1예
    Korean Journal Of Laboratory Medicine 28/4 :262-266,2008
  • 림프종 환자에서 양전자단층촬영술상 발견된 비기능성 뇌하수체선종 1예
    대한내분비학회지(Journal Of The Korean Society Of Endocrinology) 23/2 :137-141,2008
  • R-CHOP 요법으로 치료한 장기이식 후 림프증식 질환 2예
    대한혈액학회지 43/2 :6-6,2008
  • 급성골수성백혈병에서 Notch 발현의 의미
    대한혈액학회지 43/1 :9-18,2008
  • Transfusion-associated iron overload as a predictive factor for poor stem cell mobilization in patients with haematological malignancies
    Transfusion Medicine 18/ :97-103,2008
  • Acute erythroleukemia with der(1;7)(q10;p10) as a sole acquired abnormality after treatment with azathioprine
    Cancer Genetics And Cytogenetics 186/ :58-60,2008
  • Complex t(8;1.9;21)(q22;p13;q22) as a sole abnormality in a patient with de novo acute myeloid leukemia
    Cancer Genetics And Cytogenetics 185/ :109-112,2008
  • Prognostic implications of the immunophenotype in biphenotypic acute leukemia
    Leukemia & Lymphoma 49/ :700-709,2008
  • Preceding orbital granulocytic sarcoma in an adult patient with acute myelogenous leukemia with t(8;21): a case study and review of the literature
    Cancer Genetics And Cytogenetics 185/ :51-54,2008
  • Protein kinase CK2α as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia
    CLINICAL CANCER RESEARCH 13/3 :1019-1028,2007
  • Long-term outcome after prophylactic lamivudine treatment of hepatitis B virus reactivation in non-Hodgkin's lymphoma
    YONSEI MEDICAL JOURNAL 48/1 :78-89,2007
  • Therapeutic comparison of chemotherapy and surgery for early stage diffuse large B-cell gastric lymphoma
    YONSEI MEDICAL JOURNAL 48/6 :942-948,2007
  • Comparison of ataxia-telangiectasia mutated protein expression in diffuse large B-cell lymphomas of primary central nervous system and non-central nervous system origin
    ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE 131/3 :457-467,2007
  • 골수형성이상증후군에서의 임상진료지침
    대한혈액학회지 42/2 :1-1,2007
  • Treatment of Hodgkin's disease: A twenty-year follow-up of patients at a center in Korea
    YONSEI MEDICAL JOURNAL 47/4 :455-465,2006
  • 골수형성이상증후군
    대한의사협회지(Journal Of The Korean Medical Association) 49/10 :897-907,2006
  • High dose chemotherapy and autologous stem cell transplantation in non-Hodgkin's lymphoma: An eight-year experience
    YONSEI MEDICAL JOURNAL 47/5 :604-613,2006
  • 다발성 골수종 환자에서 발생한 아스페르길루스에 의한 내인성 안구내염
    대한진단검사의학회지(Korean Journal Of Legal Medicine) 26/1 :36-38,2006
  • Nine-year survival of lymphoblastic lymphoma patients
    YONSEI MEDICAL JOURNAL 47/4 :466-474,2006
  • Coronary Artery Intervention after Cytostatics Treatment in Unstable Angina Patient with Essential hrombocythemia. A Case Report and Literature Review
    The Korean Journal of Internal Medicine 21/2 :146-149,2006
  • Infused CD34+ cell dose predicts long-term survival in acute myelogenous leukemia patients who received allogeneic bone marrow transplantation from matched sibling donors in first complete remission
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 11/ :122-128,2005
  • 경구용 Steroid나 Danazol로 성공적으로 치료된 후천성혈우병 A 2예
    대한혈액학회지 40/1 :11-11,2005
  • 의식장애를 동반한 고암모니아혈증과 혈청 아미노산이상을 보인 원발성 유전분증 1예
    대한혈액학회지 40/1 :10-10,2005
  • EPO 사용이 없었던 말기신부전으로 혈액투석 중인 환자에서 발생한 적혈구증가증 1예
    The Korean Journal of Nephrology 24/4 :660-665,2005
  • Treatment of Hodgkin's Disease : A Twenty-Year Follow Up Experience of a Single Center in Korea
    YONSEI MEDICAL JOURNAL / :-,2005
  • An unusual case of spontaneous remission of Hodgkin's disease after a single cycle of COPP-ABV chemotherapy followed by infectious complications
    YONSEI MEDICAL JOURNAL 46/3 :425-430,2005
  • 특발성 호산구증가증후군 환자에서의 호산구성 뇌막염 1예
    JOURNAL OF THE KOREAN NEUROLOGICAL ASSOCIATION 23/3 :396-398,2005
  • 임신 중 동반된 급성 림프구성 백혈병 1예
    대한산부인과학회지(Korean Journal of Obstetrics and Gynecololy) 48/2 :467-472,2005
  • Apicidin potentiates the imatinib-induced apoptosis of Bcr-Abl-positive human leukaemia cells by enhancing the activation of mitochondria-dependent caspase cascades
    BRITISH JOURNAL OF HAEMATOLOGY 124/2 :166-178,2004
  • Elevated S-phase kinase-associated protein 2 protein expression in acute myelogenous leukemia: Its association with constitutive phosphorylation of phosphatase and tensin homologue protein and poor prognosis
    CLINICAL CANCER RESEARCH 10/ :5123-5130,2004
  • Isolated extramedullary relapse of acute myelogenous leukemia as a uterine granulocytic sarcoma in an allogeneic hematopoietic stem cell transplantation recipient
    YONSEI MEDICAL JOURNAL 45/2 :330-333,2004
  • Chronic graft-versus-host disease of the liver preseating as an acute hepatitis following nonmyeloablative hematopoietic stem cell transplantation
    INTERNATIONAL JOURNAL OF HEMATOLOGY 79/5 :501-504,2004
  • Cytoplasmic mislocalization of p27Kip1 protein is associated with constitutive phosphorylation of Akt or protein kinase B and poor prognosis in acute myelogenous leukemia
    CANCER RESEARCH 64/ :5225-5231,2004
  • 급성백혈병에서의 Akt 발현과 그 임상적 의의
    대한혈액학회지 38/4 :253-260,2003
  • Phosphatase and tensin homologue phosphorylation in the C-terminal regulatory domain is frequently observed in acute myeloid leukaemia and associated
    BRITISH JOURNAL OF HAEMATOLOGY 122/3 :454-456,2003
  • Constitutive phosphorylation of FKHR transcription factor as a prognostic variable in acute myeloid leukemia.
    LEUKEMIA RESEARCH 27/12 :1159-1162,2003
  • Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia: its significance as a prognostic variable.
    LEUKEMIA 17/5 :995-997,2003
  • Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.
    CLINICAL CANCER RESEARCH 9/13 :5018-5027,2003
  • Long-term bone marrow culture-derived stromal fibroblasts as a potential target for gene therapy in acute myelogenous leukemia.
    LEUKEMIA RESEARCH 26/4 :369-376,2002
  • AC133 항원 양성 급성백혈병의 생물학적 특징
    대한혈액학회지 37/3 :177-190,2002
  • Treatment of high-risk acute myelogenous leukaemia by myeloablative chemoradiotherapy followed by co-infusion of T cell-depleted haematopoietic stem c
    BRITISH JOURNAL OF HAEMATOLOGY 118/4 :1128-1131,2002
  • 의식장애를 동반한 고암모니아혈증과 혈청 아미노산 이상을 보인 다발성골수종 1례
    대한혈액학회지 0/0 :84-87,2002
  • NK/T 세포 림프종 환자에서 시행된 비골수제거성 조혈모세포이식
    대한조혈모세포이식학회지 6/2 :229-236,2001
  • 크론씨병에 동반된 골수이형성증후군 2례
    대한혈액학회지 37/1 :70-75,2001
  • 동종 조혈모세포이식 후 급성 이식편대 숙주반응 시 T 세포의 OX-40 표현
    대한조혈모세포이식학회지 5/2 :211-222,2000

저서

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  • Early response to high-dose methotrexate, vincristine, and procarbazine chemotherapy-adapted strategy for primary CNS lymphoma: no consolidation therapy for patients achieving early complete response. ANNALS OF HEMATOLOGY 211~219 2014/02
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  • Clinical Outcomes and Prognostic Factors of Empirical Antifungal Therapy with Itraconazole in the Patients with Hematological Malignancies: A Prospective Multicenter Observational Study in Korea YONSEI MEDICAL JOURNAL 9~18 2014/01
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  • Diagnostic Accuracy of Cerebrospinal Fluid (CSF) Cytology in Metastatic Tumors: An Analysis of Consecutive CSF Samples KOREAN JOURNAL OF PATHOLOGY 563~568 2013/12
  • Patterns of care and treatment outcomes for primary thyroid lymphoma: a single institution study Radiation oncology journal 177~184 2013/12
  • Comparative analysis between azacitidine and decitabine for the treatment of myelodysplastic syndromes BRITISH JOURNAL OF HAEMATOLOGY 339~347 2013/05
  • 항체동정검사상 범응집반응을 보인 환자에서 최소반응강도 적혈구제제의 수혈 효과 대한수혈학회지 48~57 2013/04
  • Influence of enzyme and transporter polymorphisms on trough imatinib concentration and clinical response in chronic myeloid leukemia patients ANNALS OF ONCOLOGY 756~760 2013/03
  • Karyotypic change between diagnosis and relapse as a predictor of salvage therapy outcome in AML patients. Blood Research 24~30 2013/03
  • Fludarabine, cytarabine, and attenuated-dose idarubicin (m-FLAI) combination therapy for elderly acute myeloid leukemia patients AMERICAN JOURNAL OF HEMATOLOGY 10~15 2013/01
  • Aurora A kinase expression is increased in leukemia stem cells, and a selective Aurora A kinase inhibitor enhances Ara-C-induced apoptosis in acute myeloid leukemia stem cells 대한혈액학회지 178~185 2012/09
  • A randomized trial of mesenchymal stem cells in multiple system atrophy. ANNALS OF NEUROLOGY 32~40 2012/07
  • Patient counseling program to improve the compliance to imatinib in chronic myeloid leukemia patients MEDICAL ONCOLOGY 1179~1185 2012/06
  • Risk Factors for Progression from Cytomegalovirus Viremia to Cytomegalovirus Disease after Allogeneic Hematopoietic Stem Cell Transplantation BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 881~886 2012/06
  • Myeloperoxidase expression in acute myeloid leukemia helps identifying patients to benefit from transplant. YONSEI MEDICAL JOURNAL 530~536 2012/05
  • Clinical significance of B cell-activating factor (BAFF) and a proliferation-inducing ligand (APRIL) in acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation 대한혈액학회지 175~179 2011/09
  • Lymphopenia is an important prognostic factor in peripheral T-cell lymphoma (NOS) treated with anthracycline-containing chemotherapy JOURNAL OF HEMATOLOGY & ONCOLOGY 2011/08
  • Trough plasma imatinib levels are correlated with optimal cytogenetic responses at 6 months after treatment with standard dose of imatinib in newly diagnosed chronic myeloid leukemia LEUKEMIA & LYMPHOMA 1024~1029 2011/06
  • Cytogenetic features of 5q deletion and 5q-syndrome in myelodysplastic syndrome in Korea; marker chromosomes proved to be chromosome 5 with interstitial deletion by fluorescence in situ hybridization Cancer Genetics and Cytogenetics 193~202 2010/12
  • Myeloperoxidase Expression as a Potential Determinant of Parthenolide-Induced Apoptosis in Leukemia Bulk and Leukemia Stem Cells Journal Of Pharmacology And Experimental Therapeutics 389~400 2010/11
  • Inhibition of CK2 alpha and PI3K/Akt Synergistically Induces Apoptosis of CD34(+)CD38(-) Leukaemia Cells while Sparing Haematopoietic Stem Cells Anticancer Research 4625~4634 2010/11
  • AURORA-A KINASE INHIBITION ENHANCES THE CYTOSINE ARABINOSIDE-INDUCED CELL DEATH IN LEUKEMIA CELLS THROUGH APOPTOSIS AND MITOTIC CATASTROPHE Haematologica-The Hematology Journal 1771~ 2010/06
  • Detection of FUS-ERG chimeric transcript in two cases of acute myeloid leukemia with t(16;21)(p11.2;q22) with unusual characteristics Cancer Genetics and Cytogenetics 111~118 2009/10
  • Natural polyphenols antagonize the antimyeloma activity of proteasome inhibitor bortezomib by direct chemical interaction British Journal Of Haematology 270~281 2009/08
  • Therapy-related myelodysplastic syndrome with der(17)t(12;17)(q13;p13) as a new recurrent cytogenetic abnormality after treatment for chronic lymphocytic leukemia Leukemia Research 1001~1004 2009/07
  • Two case reports of 1q triplication in myeloproliferative neoplasms Cancer Genetics and Cytogenetics 111~112 2009/06
  • Complete Remission Status before Autologous Stem Cell Transplantation Is an Important Prognostic Factor in Patients with Multiple Myeloma Undergoing Upfront Single Autologous Transplantation Biology Of Blood And Marrow Transplantation 463~470 2009/04
  • A successful treatment of relapsed primary CNS lymphoma patient with intraventricular rituximab followed by high-dose chemotherapy with autologous stem cell rescue Yonsei Medical Journal 280~283 2009/04
  • 동종 조혈모세포이식 후 다발성 근염으로 발현된 만성 이식편대숙주반응 대한내과학회지 110~113 2009/01
  • Concomitant t(3;3)(q21;q26), trisomy 19, and E255V mutation associated with imatinib mesylate resistance in chronic myelogenous leukemia Cancer Genetics and Cytogenetics 46~48 2009/01
  • Complex t(8;1.9;21)(q22;p13;q22) as a sole abnormality in a patient with de novo acute myeloid leukemia Cancer Genetics And Cytogenetics 109~112 2008/09
  • Preceding orbital granulocytic sarcoma in an adult patient with acute myelogenous leukemia with t(8;21): a case study and review of the literature Cancer Genetics And Cytogenetics 51~54 2008/08
  • 8번 염색체 사체성을 보인 급성단구성백혈병 1예 Korean Journal Of Laboratory Medicine 262~266 2008/08
  • R-CHOP 요법으로 치료한 장기이식 후 림프증식 질환 2예 대한혈액학회지 6~6 2008/06
  • 림프종 환자에서 양전자단층촬영술상 발견된 비기능성 뇌하수체선종 1예 대한내분비학회지(Journal Of The Korean Society Of Endocrinology) 137~141 2008/04
  • 급성골수성백혈병에서 Notch 발현의 의미 대한혈액학회지 9~18 2008/03
  • Prognostic implications of the immunophenotype in biphenotypic acute leukemia Leukemia & Lymphoma 700~709 2008/01
  • Acute erythroleukemia with der(1;7)(q10;p10) as a sole acquired abnormality after treatment with azathioprine Cancer Genetics And Cytogenetics 58~60 2008/01
  • Transfusion-associated iron overload as a predictive factor for poor stem cell mobilization in patients with haematological malignancies Transfusion Medicine 97~103 2008/01
  • Transfusion-Associated Iron Overload as an Adverse Risk Factor for Transplantation Outcome in Patients Undergoing Reduced-Intensity Stem Cell Transplantation for Myeloid Malignancies Acta Haematologica 182~189 2008/01
  • 골수형성이상증후군에서의 임상진료지침 대한혈액학회지 1~1 2007/06
  • Comparison of ataxia-telangiectasia mutated protein expression in diffuse large B-cell lymphomas of primary central nervous system and non-central nervous system origin ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE 457~467 2007/03
  • Therapeutic comparison of chemotherapy and surgery for early stage diffuse large B-cell gastric lymphoma YONSEI MEDICAL JOURNAL 942~948 2007/01
  • Long-term outcome after prophylactic lamivudine treatment of hepatitis B virus reactivation in non-Hodgkin's lymphoma YONSEI MEDICAL JOURNAL 78~89 2007/01
  • Protein kinase CK2α as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia CLINICAL CANCER RESEARCH 1019~1028 2007/01
  • High dose chemotherapy and autologous stem cell transplantation in non-Hodgkin's lymphoma: An eight-year experience YONSEI MEDICAL JOURNAL 604~613 2006/10
  • Nine-year survival of lymphoblastic lymphoma patients YONSEI MEDICAL JOURNAL 466~474 2006/08
  • Treatment of Hodgkin's disease: A twenty-year follow-up of patients at a center in Korea YONSEI MEDICAL JOURNAL 455~465 2006/08
  • Coronary Artery Intervention after Cytostatics Treatment in Unstable Angina Patient with Essential hrombocythemia. A Case Report and Literature Review The Korean Journal of Internal Medicine 146~149 2006/06
  • 다발성 골수종 환자에서 발생한 아스페르길루스에 의한 내인성 안구내염 대한진단검사의학회지(Korean Journal Of Legal Medicine) 36~38 2006/02
  • 골수형성이상증후군 대한의사협회지(Journal Of The Korean Medical Association) 897~907 2006/01
  • EPO 사용이 없었던 말기신부전으로 혈액투석 중인 환자에서 발생한 적혈구증가증 1예 The Korean Journal of Nephrology 660~665 2005/07
  • 특발성 호산구증가증후군 환자에서의 호산구성 뇌막염 1예 JOURNAL OF THE KOREAN NEUROLOGICAL ASSOCIATION 396~398 2005/06
  • 의식장애를 동반한 고암모니아혈증과 혈청 아미노산이상을 보인 원발성 유전분증 1예 대한혈액학회지 10~10 2005/03
  • 경구용 Steroid나 Danazol로 성공적으로 치료된 후천성혈우병 A 2예 대한혈액학회지 11~11 2005/03
  • 임신 중 동반된 급성 림프구성 백혈병 1예 대한산부인과학회지(Korean Journal of Obstetrics and Gynecololy) 467~472 2005/02
  • An unusual case of spontaneous remission of Hodgkin's disease after a single cycle of COPP-ABV chemotherapy followed by infectious complications YONSEI MEDICAL JOURNAL 425~430 2005/01
  • Treatment of Hodgkin's Disease : A Twenty-Year Follow Up Experience of a Single Center in Korea YONSEI MEDICAL JOURNAL 2005/01
  • Infused CD34+ cell dose predicts long-term survival in acute myelogenous leukemia patients who received allogeneic bone marrow transplantation from matched sibling donors in first complete remission BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 122~128 2005/01
  • Chronic graft-versus-host disease of the liver preseating as an acute hepatitis following nonmyeloablative hematopoietic stem cell transplantation INTERNATIONAL JOURNAL OF HEMATOLOGY 501~504 2004/06
  • Isolated extramedullary relapse of acute myelogenous leukemia as a uterine granulocytic sarcoma in an allogeneic hematopoietic stem cell transplantation recipient YONSEI MEDICAL JOURNAL 330~333 2004/04
  • Cytoplasmic mislocalization of p27Kip1 protein is associated with constitutive phosphorylation of Akt or protein kinase B and poor prognosis in acute myelogenous leukemia CANCER RESEARCH 5225~5231 2004/01
  • Elevated S-phase kinase-associated protein 2 protein expression in acute myelogenous leukemia: Its association with constitutive phosphorylation of phosphatase and tensin homologue protein and poor prognosis CLINICAL CANCER RESEARCH 5123~5130 2004/01
  • Apicidin potentiates the imatinib-induced apoptosis of Bcr-Abl-positive human leukaemia cells by enhancing the activation of mitochondria-dependent caspase cascades BRITISH JOURNAL OF HAEMATOLOGY 166~178 2004/01
  • Constitutive phosphorylation of FKHR transcription factor as a prognostic variable in acute myeloid leukemia. LEUKEMIA RESEARCH 1159~1162 2003/12
  • 급성백혈병에서의 Akt 발현과 그 임상적 의의 대한혈액학회지 253~260 2003/11
  • Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells. CLINICAL CANCER RESEARCH 5018~5027 2003/10
  • Phosphatase and tensin homologue phosphorylation in the C-terminal regulatory domain is frequently observed in acute myeloid leukaemia and associated BRITISH JOURNAL OF HAEMATOLOGY 454~456 2003/08
  • Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia: its significance as a prognostic variable. LEUKEMIA 995~997 2003/05
  • Treatment of high-risk acute myelogenous leukaemia by myeloablative chemoradiotherapy followed by co-infusion of T cell-depleted haematopoietic stem c BRITISH JOURNAL OF HAEMATOLOGY 1128~1131 2002/09
  • AC133 항원 양성 급성백혈병의 생물학적 특징 대한혈액학회지 177~190 2002/08
  • Long-term bone marrow culture-derived stromal fibroblasts as a potential target for gene therapy in acute myelogenous leukemia. LEUKEMIA RESEARCH 369~376 2002/04
  • 의식장애를 동반한 고암모니아혈증과 혈청 아미노산 이상을 보인 다발성골수종 1례 대한혈액학회지 84~87 2002/01
  • NK/T 세포 림프종 환자에서 시행된 비골수제거성 조혈모세포이식 대한조혈모세포이식학회지 229~236 2001/12
  • 크론씨병에 동반된 골수이형성증후군 2례 대한혈액학회지 70~75 2001/10
  • 동종 조혈모세포이식 후 급성 이식편대 숙주반응 시 T 세포의 OX-40 표현 대한조혈모세포이식학회지 211~222 2000/12

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