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진료과

  • 어린이병원-소아내분비과

전문진료분야

  • 저신장, 당뇨병, 성조숙증, 갑상선질환, 비만

진료시간표

전화예약만 가능1599-1004
의사시간표
진료시간
오전 어린이병원
오후 어린이병원 어린이병원 어린이병원

교육 및 임상 경력

  • 1991-1993  소아내분비학  연구강사
  • 1993-1995  이화의대  소아과학  전임강사
  • 1995-1999  이화의대  소아과학  조교수
  • 1999-2003  미국  Oregon  Health  &  Science  University  소아과  senior  researcher
  • 2003-2006  연세의대  소아과학교실  부교수
  • 2007-현재  연세의대  소아과학교실  교수

학술관련경력

  • 1991-현재 대한소아과학회 회원
  • 1991-현재 대한내분비학회 회원
  • 1991-현재 대한당뇨병학회 회원
  • 1991-현재 대한소아내분비학회 회원
  • 1997-현재 미국 Endocrine Society 회원
  • 2001-현재 International Society for IGF Research 회원
  • 2004-현재 American Diabetes Association 회원
  • *동아일보 선정 소아 질환분야 베스트 닥터(2000)

주요 관심분야

  • 저신장, 소아당뇨, 비만, 갑상선질환, 부신질환
  • 유방암과 소아암에서 인슐린양성장인자 결합단백질(Insulin-like growth factor binding protein)-3와 그 수용체(receptor)의 기능과 기전(apoptosis & cell signaling)
  • 당뇨합병증 발생에서 결합조직 성장인자(connective tissue growth factor)와 인슐린양성장인자 결합단백질 (IGFBP)의 역할
  • 저신장 유발 유전자의 규명

학력사항

  • 연세대학교 의과대학 의학과 학사(1984)
  • 연세대학교 대학원 의학과 석사(1991)
  • 연세대학교 대학원 의학과(소아과학) 박사 (1995)

논문

  • Insulin-like growth factor-binding protein 3 induces caspase-dependent apoptosis through a death receptor-mediated pathway in MCF-7 human breast cancer cells. Cancer Res 64:2229-2237, 2004
  • Effect of intense exercise on inflammatory cytokines and growth mediators in adolescent boys. Pediatrics 110:681-689, 2002
  • Connective tissue growth factor/IGF-binding protein-related protein-2 is a mediator in the induction of fibronectin by advanced glycosylation end-products in human dermal fibroblasts. Endocrinol 143:1260-1269, 2002.
  • Effects of sodium butyrates on expression of members of the insulin-like growth factor binding protein superfamily in human mammary epithelial cells. J Endocrinol 169:97-110, 2001
  • Advanced glycosylation end-products up-regulate connective tissue growth factor (IGFBP-rP2) in human fibroblast.; a potential mechanism for expansion of extracellular matrix in diabetes mellitus. Endocrinol 142:1760-1769, 2001
  • Serum levels of insulin-like growth factor (IGF)-I, free IGF-I, IGF binding protein (IGFBP)-1, IGFBP-3 and insulin in obese children. J Pediatr Endocrinol Metab 12:139-144, 1999
  • Identification of glycosylated 38-kDa connective tissue growth factor (IGFBP-related protein 2) and proteolytic fragments in human biological fluids, and up-regulation of IGFBP-rP2 expression by TGF in Hs 578T human breast cancer cells. J Clin Endocr Metab 83:2593-2596, 1998
  • Identification of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily. Proc Natl Acad Sci USA 94: 12981-12986, 1997
  • Biological roles of insulin-like growth factor binding proteins (IGFBPs). Exp Mol Med 29:85-96, 1997
  • Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7. J Biol Chem 271: 30322-30325, 1996
  • 성장호르몬 결핍증과 특발성 저신장증 환아에서 성장호르몬의 치료 효과
    KOREAN JOURNAL OF PEDIATRICS 47/3 :310-316,2004
  • 소아비만증에서 대사 증후군의 유병률
    KOREAN JOURNAL OF PEDIATRICS 47/11 :1149-1156,2004
  • 소아 제 2형 당뇨병 환아에서 Maturity Onset Diabetes of the Young(MODY) 3의 유병률에 관한 연구
    KOREAN JOURNAL OF PEDIATRICS 47/6 :641-,2004
  • 소아기 후천성 갑상선질환
    소아과(Korean Journal of Pediatrics) 47/9 :926-932,2004
  • Insulin-LIke Growth Factor-Binding Protein 3 Induces Caspase-Dependent Apoptosis through a Death Receptor-Mediated pathway in MCF-7 Human Breast Caner Cells
    CANCER RESEARCH 64/ :2229-2237,2004
  • The abnormalities of carbohydrate metabolism in Turner syndrome: Analysis of risk factors associated with impaired glucose tolerance
    EUROPEAN JOURNAL OF PEDIATRICS 164/ :442-447,2005
  • 소아 및 청소년 비만증에서 인슐린 저항성의 성별 차이
    대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 10/1 :84-89,2005
  • 정상변이 염색체 다형현상과 동반된 저신장증
    대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 10/1 :95-99,2005
  • 소아 및 청소년 비만증에서 인슐린 저항성에 미치는 요인
    소아과(Korean Journal Of Pediatrics) 48/10 :1076-1081,2005
  • 소아 비만증에서 비알코올성 지방간염의 유병률
    Korean Journal of Pediatrics 48/1 :13-20,2005
  • 한국인 선천성 부신피질과형성증의 임상적 특성
    대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 10/2 :132-137,2005
  • 단순비만아에서 비만이 혈중 성장인자와 인슐린양성인자결합단백질-3의 단백분해에 미치는 영향
    대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 10/2 :1995-203,2005
  • Obesity and cardiovascular risk factors in Korean children and adolescents aged 10-18 years from the Korean National Health and Nutrition Examination Survey, 1998 and 2001
    AMERICAN JOURNAL OF EPIDEMIOLOGY 164/8 :787-793,2006
  • 특발성 저신장증 환자에서 성장 호르몬 투여가 당 대사에 미치는 영향
    대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 49/6 :665-671,2006
  • Association of Henoch-Scho?nlein purpura and Graves' disease [12]
    NEPHROLOGY DIALYSIS TRANSPLANTATION 21/ :2997-,2006
  • 조기 사춘기 여아에서 성선자극호르몬 분비호르몬 유도체가 성장과 성호르몬에 미치는 효과
    대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 11/2 :162-169,2006
  • 소아에서 혈중 아연 농도가 성장에 미치는 영향
    대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 11/2 :155-161,2006
  • Prevalence of the metabolic syndrome in Korean adolescents aged 12-19 years from the Korean National Health and Nutrition Examination Survey 1998 and 2001
    DIABETES RESEARCH AND CLINICAL PRACTICE 75/ :111-114,2007
  • 1형 당뇨병을 가진 소아과 청소년에서 란투스 치료의 혈당 조절에 대한 효과
    소아과(Korean Journal Of Pediatrics) 50/6 :565-569,2007
  • 뇌종양 환아에서 성장호르몬 치료 후 뇌종양 재발증가에 관한 연구
    대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 12/2 :99-103,2007
  • 성조숙증 아동의 임상 및 내분비 검사의 특징
    대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 12/2 :119-126,2007
  • 성조숙증의 진단과 최신 치료 경향
    대한내분비학회지(Journal Of The Korean Society Of Endocrinology) 23/3 :165-173,2008
  • 당뇨병성 신증의 조기 예측 인자로서의 혈중 cystatin C 및 β2-microglobulin의 유용성
    대한소아내분비학회지(Journal Of Korean Society Of Pediatric Endocrinology) 13/2 :177-183,2008
  • 소아 뇌종양 수술 후 수분대사 및 전해질 장애
    Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 14/2 :124-131,2009
  • 1형 당뇨병 환자에서 생리주기 이상
    Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 14/2 :116-123,2009
  • Determination of Serum Di-(2-ethylhexyl) phthalate and Bisphenol A Level in Children with Idiopathic Central Precocious Puberty
    Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 14/2 :154-162,2009
  • Clinical application of gonadotropin-releasing hormone analogs in children and adolescents
    Korean Journal of Pediatrics 53/3 :294-299,2010
  • Insulin-like Growth Factor Binding Protein-3 Induces G1 Cell Cycle Arrest with Inhibition of Cyclin-dependent Kinase 2 and 4 in MCF-7 Human Breast Cancer Cells
    Hormone And Metabolic Research 42/3 :165-172,2010
  • 터너증후군에서 성장호르몬과 성호르몬 치료에 따른 인슐린 저항성의 변화
    Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 15/1 :44-50,2010
  • An SRY-Deleted XXY Female Resulting from a Paternally Inherited t(Y;22)
    Annals of Clinical and Laboratory Science 40/3 :295-299,2010
  • Two Cases of Multiple Endocrine Neoplasia Type 2B, Early Diagnosis by Genetic Analysis and Prophylactic Total Thyroidectomy
    Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 15/2 :138-144,2010
  • 소아청소년 연령에서 발생한 2형 당뇨병의 항췌도 자가항체 유무에 따른 임상적 특성
    Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 15/2 :93-99,2010
  • Identification of a Novel Cell Death Receptor Mediating IGFBP-3-induced Anti-tumor Effects in Breast and Prostate Cancer
    The Journal of biological chemistry 285/39 :30233-30246,2010
  • Effects of a Structured Exercise Program on Insulin Resistance, Inflammatory Markers and Physical Fitness in Obese Korean Children
    Journal of Pediatric Endocrinology & Metabolism 23/10 :1065-1072,2010
  • 부갑상샘저하증과 거짓 부갑상샘저하증의 임상적 특성
    Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 15/3 :181-186,2010
  • 1형 당뇨병 소아환자에서 발생한 원발성 국소분절사구체경화증 1례
    Journal Of Korean Society Of Pediatric Endocrinology(대한소아내분비학회지) 15/3 :203-206,2010
  • Effects of Body Composition, Leptin, and Adiponectin on Bone Mineral Density in Prepubertal Girls
    JOURNAL OF KOREAN MEDICAL SCIENCE 25/8 :1187-1190,2010
  • Noonan 증후군과 성장호르몬결핍증 환아에서 성장호르몬 치료 효과
    대한소아내분비학회지 16/2 :100-105,2011
  • Serum Kisspeptin Levels in Korean Girls with Central Precocious Puberty
    JOURNAL OF KOREAN MEDICAL SCIENCE 26/7 :927-931,2011
  • Insulin-Like Growth Factor-Binding Protein-3 Mediates High Glucose-Induced Apoptosis by Increasing Oxidative Stress in Proximal Tubular Epithelial Cells
    ENDOCRINOLOGY 152/8 :3135-3142,2011
  • Frequencies and Related Factors for Microvascular Complications in Patients with Type 1 Diabetes
    Annals of Pediatric Endocrinology & Metabolism 17/1 :16-26,2012
  • Reference values for serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in Korean children and adolescents
    CLINICAL BIOCHEMISTRY 45/1-2 :16-21,2012
  • Spot urine albumin to creatinine ratio and serum cystatin C are effective for detection of diabetic nephropathy in childhood diabetic patients
    JOURNAL OF KOREAN MEDICAL SCIENCE 27/7 :784-787,2012
  • Hypodipsic hypernatremia leading to reversible renal failure following surgery for craniopharyngioma
    JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM 25/9-10 :1027-1030,2012
  • Proton-Pump Inhibitor-Induced Hypocalcemia and Hypomagnesemia
    대한소아내분비학회지 17/4 :249-252,2012
  • IGFBP-3 Inhibits Cytokine-Induced Insulin Resistance and Early Manifestations of Atherosclerosis
    PLOS ONE 8/1 :e55084-e55084,2013
  • Longitudinal Standards for Height and Height Velocity in Korean Children and Adolescents: the Kangwha Cohort Study
    JOURNAL OF KOREAN MEDICAL SCIENCE 28/10 :1512-1517,2013
  • The Clinical Measures Associated with C-peptide Decline in Patients with Type 1 Diabetes over 15 Years
    JOURNAL OF KOREAN MEDICAL SCIENCE 28/9 :1340-1344,2013
  • Final height and insulin-like growth factor-1 in children with medulloblastoma treated with growth hormone
    CHILDS NERVOUS SYSTEM 29/10 :1859-1863,2013
  • Efficacy and safety of LB03002, a once-weekly sustained-release human GH for 12-month treatment in Korean children with GH deficiency
    EUROPEAN JOURNAL OF ENDOCRINOLOGY 169/2 :179-185,2013
  • Sex hormone binding globulin, free estradiol index, and lipid profiles in girls with precocious puberty
    Annals of Pediatric Endocrinology & Metabolism 18/2 :81-84,2013
  • Factors that predict a positive response on gonadotropin-releasing hormone stimulation test for diagnosing central precocious puberty in girls
    Annals of Pediatric Endocrinology & Metabolism 18/4 :202-207,2013
  • Role of insulin-like growth factor binding protein-3 in glucose and lipid metabolism
    Annals of Pediatric Endocrinology & Metabolism 18/1 :9-12,2013
  • Efficacy of Short-Term Growth Hormone Treatment in Prepubertal Children with Idiopathic Short Stature
    YONSEI MEDICAL JOURNAL 55/1 :53-60,2014
  • Establishing pediatric reference intervals for 13 biochemical analytes derived from normal subjects in a pediatric endocrinology clinic in Korea
    CLINICAL BIOCHEMISTRY 47/18 :268-271,2014
  • KISS1 Gene Polymorphisms in Korean Girls with Central Precocious Puberty
    JOURNAL OF KOREAN MEDICAL SCIENCE 29/8 :1120-1125,2014
  • A case of thyrotoxic periodic paralysis as initial manifestation of Graves' disease in a 16-year-old Korean adolescent
    Annals of Pediatric Endocrinology & Metabolism 19/3 :169-173,2014
  • Adult height in girls with central precocious puberty treated with gonadotropin-releasing hormone agonist with or without growth hormone
    Annals of Pediatric Endocrinology & Metabolism 19/4 :214-219,2014
  • Growth hormone treatment and risk of malignancy
    Korean Journal of Pediatrics 58/2 :41-46,2015
  • Regression and progression of microalbuminuria in adolescents with childhood onset diabetes mellitus
    Annals of Pediatric Endocrinology & Metabolism 20/1 :13-20,2015
  • Etiologies and characteristics of children with chief complaint of short stature
    Annals of Pediatric Endocrinology & Metabolism 20/1 :34-39,2015
  • Relationship between serum 25-hydroxyvitamin D concentration and risks of metabolic syndrome in children and adolescents from Korean National Health and Nutrition Examination survey 2008?2010
    Annals of Pediatric Endocrinology & Metabolism 20/1 :46-52,2015
  • Clinical manifestations of testicular adrenal rest tumor in males with congenital adrenal hyperplasia
    Annals of Pediatric Endocrinology & Metabolism 20/3 :155-161,2015
  • Hypotonic hyponatremia by primary polydipsia caused brain death in a 10-year-old boy
    Annals of Pediatric Endocrinology & Metabolism 20/3 :166-169,2015
  • XYY syndrome: a 13-year-old boy with tall stature
    Annals of Pediatric Endocrinology & Metabolism 20/3 :170-173,2015
  • Turner syndrome with spinal hemorrhage due to vascular malformation
    Annals of Pediatirc Endocrinology & Metabolism 20/4 :235-237,2015
  • Burkholderia Sepsis in Children as a Hospital-Acquired Infection
    YONSEI MEDICAL JOURNAL 57/1 :97-102,2016
  • Ultrasound measurement of pediatric visceral fat thickness: correlations with metabolic and liver profiles
    Annals of Pediatirc Endocrinology & Metabolism 21/2 :75-80,2016
  • Male patients presenting with rapidly progressive puberty associated with malignant tumors.
    Annals of Pediatric Endocrinology & Metabolism 21/1 :51-55,2016
  • A patient with Cushing disease lateralizing a pituitary adenoma by inferior petrosal sinus sampling using desmopressin
    Annals of Pediatric Endocrinology & Metabolism 21/1 :43-46,2016
  • Human Coronavirus in the 2014 Winter Season as a Cause of Lower Respiratory Tract Infection
    YONSEI MEDICAL JOURNAL 58/1 :174-179,2017
  • Elevated serum YKL-40 levels in patients with Kawasaki disease
    BIOMARKERS 22/3-4 :326-330,2017
  • Diabetes mellitus due to agenesis of the dorsal pancreas in a patient with heterotaxy syndrome
    Annals of Pediatirc Endocrinology & Metabolism 22/2 :125-128,2017
  • Risk of Gonadoblastoma Development in Patients with Turner Syndrome with Cryptic Y Chromosome Material
    HORMONES & CANCER 8/3 :166-173,2017
  • Clinical manifestations of Rathke’s cleft cysts and their natural progression during 2 years in children and adolescents
    Annals of Pediatirc Endocrinology & Metabolism 22/3 :164-169,2017
  • A 1-month-old infant with chylomicronemia due to GPIHBP1 gene mutation treated by plasmapheresis
    Annals of Pediatirc Endocrinology & Metabolism 22/1 :68-71,2017
  • Insulin resistance and bone age advancement in girls with central precocious puberty
    Annals of Pediatirc Endocrinology & Metabolism 22/3 :176-182,2017
  • A boy with 46,X,+mar presenting gynecomastia and short stature
    Annals of Pediatirc Endocrinology & Metabolism 22/4 :266-271,2017
  • Once-Weekly Administration of Sustained-Release Growth Hormone in Korean Prepubertal Children with Idiopathic Short Stature: A Randomized, Controlled Phase II Study
    HORMONE RESEARCH IN PAEDIATRICS 90/1 :54-63,2018
  • Visceral fat thickness and its associations with pubertal and metabolic parameters among girls with precocious puberty
    Annals of Pediatirc Endocrinology & Metabolism 23/2 :81-87,2018
  • Respiratory failure in a diabetic ketoacidosis patient with severe hypophosphatemia
    Annals of Pediatirc Endocrinology & Metabolism 23/2 :103-106,2018
  • Effect of Growth Hormone Therapy on Height Velocity in Korean Children with Idiopathic Short Stature: A Phase III Randomised Controlled Trial
    HORMONE RESEARCH IN PAEDIATRICS 90/1 :44-53,2018
  • Recombinant growth hormone therapy for prepubertal children with idiopathic short stature in Korea: a phase III randomized trial
    JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION 41/4 :475-483,2018
  • Effect of the Orally Active Growth Hormone Secretagogue MK-677 on Somatic Growth in Rats
    YONSEI MEDICAL JOURNAL 59/10 :1,174-1,180,2018
  • Incidence and Prevalence of Central Precocious Puberty in Korea: An Epidemiologic Study Based on a National Database
    JOURNAL OF PEDIATRICS 208/18 :221-228,2019
  • Long-term safety and effectiveness of growth hormone therapy in Korean children with growth disorders: 5-year results of LG Growth Study
    PLOS ONE 14/5 :e0216927-,2019
  • 제1형 당뇨병 청소년의 자기관리 영향요인: 정보-동기-행동기술 모델을 기반으로
    Child Health Nursing Research 25/2 :234-243,2019
  • Fructose-1,6-bisphosphatase deficiency presented with complex febrile convulsion
    NEUROENDOCRINOLOGY LETTERS 39/8 :533-536,2019
  • The analysis of endocrine disruptors in patients with central precocious puberty
    BMC PEDIATRICS 19/1 :e323-,2019
  • Final Adult Height after Growth Hormone Treatment in Patients with Turner Syndrome
    HORMONE RESEARCH IN PAEDIATRICS 91/6 :373-379,2019
  • Healthcare transition readiness, family support, and self-management competency in Korean emerging adults with Type 1 diabetes mellitus
    JOURNAL OF PEDIATRIC NURSING-NURSING CARE OF CHILDREN & FAMILIES 48/ :e1-e7,2019

김호성

진료철학
저신장, 소아당뇨, 소아비만, 소아 갑상선질환, 소아 부신질환 등에 깊은 관심을 갖고 지속적인 연구와 임상치료를 실시하고 있으며 미국 오리곤 헬스&사이언스 대학교 연수를 통해 관련 분야의 새로운 임상기술을 습득 했습니다. 현재 소아내분비클리닉(저신장증, 성장장애, 소아당뇨, 소아비만, 갑상선질환, 부신질환 등)을 운영하고 있으며 성장장애, 당뇨병, 종양(유방암) 분야에서 성장호르몬, 인슐린양 성장인자, 인슐린양 성장인자 결합단백질에 대한 많은 연구 경험을 토대로 우수 논문을 발표하고 있습니다. 소아내분비클리닉 홈페이지(www.yonseipedi.com) 운영을 통해 국민들에게 소아청소년 질환에 대한 양질의 정보를 제공 합니다.

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